tag:blogger.com,1999:blog-3352166344614826568.post7386049991585310008..comments2024-03-14T10:07:59.760-07:00Comments on American Alpine Institute - Climbing Blog: Diamox - The Wonder Drug?Erin-Leigh Hardyhttp://www.blogger.com/profile/10781785451497618508noreply@blogger.comBlogger8125tag:blogger.com,1999:blog-3352166344614826568.post-3882578763694548032012-11-05T12:02:50.729-08:002012-11-05T12:02:50.729-08:00Jason's post above is the first time I've ...Jason's post above is the first time I've personally heard of this option...<br /><br />JasonJason Martinhttps://www.blogger.com/profile/00545776792926716502noreply@blogger.comtag:blogger.com,1999:blog-3352166344614826568.post-91523078802905520172012-11-02T19:21:51.193-07:002012-11-02T19:21:51.193-07:00OK, I have to ask the obvious question. What is in...OK, I have to ask the obvious question. What is in Mountain Might that has been shown to be effective in published studies in reputable journals?Glennoreply@blogger.comtag:blogger.com,1999:blog-3352166344614826568.post-61693957233489918412012-11-02T19:17:58.069-07:002012-11-02T19:17:58.069-07:00Sadly, those promising early Ginkgo biloba finding...Sadly, those promising early Ginkgo biloba findings have not been supported in newer better studies. Acetazolamide, in spite of its many shortcomings, appears to be still the best bet for those prone to the disease. Dexamethasone is also a possibility, particularly for those with a sulfa allergy preventing them from taking acetazolamide.Glennoreply@blogger.comtag:blogger.com,1999:blog-3352166344614826568.post-82965136154019572452012-10-31T08:51:43.026-07:002012-10-31T08:51:43.026-07:00There are various studies that suggest Ginkgo Bilo...There are various studies that suggest Ginkgo Biloba does alleviate AMS. I do not have links to them, but they are available in the book Altitude Training and Athletic Performance by Randall Wilber. Jason Keckhttp://mountainmight.comnoreply@blogger.comtag:blogger.com,1999:blog-3352166344614826568.post-56538832302634034842012-10-31T08:46:45.715-07:002012-10-31T08:46:45.715-07:00Great post, I really appreciate your conservative ...Great post, I really appreciate your conservative guidelines for when to take Diamox. There are a few other caveats to taking this drug for altitude acclimatization that I would like to mention. First, just to reiterate the risk of dehydration is roughly double for every 4,000 feet of elevation and, as you stated, dehydration can exacerbate altitude sickness. Low doses (125 mg) may allow climbers to avoid this risk.<br /><br />Another potential side effect of Diamox that nobody ever talks about is that its ability to increase blood acidity may stunt hematological acclimatization. High blood acidity is proven to reduce levels of EPO in the blood. Elite altitude training programs always incorporate controls to reduce lactic acid production for this reason. <br /><br />Finally, there are a few studies that suggest though Diamox may reduce AMS, it may have a negative impact on athletic performance at high altitude. <br /><br />I work for Alpine Performance Laboratories. Our company has recently developed a supplement that allows athletes to pre-acclimatize their bodies to high altitude. Our product is called Mountain Might and it is about to release in 2 weeks. Feel free to contact us through our website for free samples or to talk with our high altitude physiology experts.<br /><br />Thanks,<br /><br />Jason<br /><br /><br />Jason Keckhttp://mountainmight.comnoreply@blogger.comtag:blogger.com,1999:blog-3352166344614826568.post-82479291156907941222012-10-30T10:28:02.309-07:002012-10-30T10:28:02.309-07:00When taking any supplement/medication to counter t...When taking any supplement/medication to counter the effects of altitude the person has to ensure they have enough for the trip plus extra. You may weathered in for exteneded periods. The sudden removal of the medication/suppliment can cause rebound effects that can go right to life threatening very rapidly.Anonymoushttps://www.blogger.com/profile/13189519624917494876noreply@blogger.comtag:blogger.com,1999:blog-3352166344614826568.post-90718543630303449412012-10-29T14:36:56.244-07:002012-10-29T14:36:56.244-07:00Sorry, which research are you pointing too?
Ginkg...Sorry, which research are you pointing too?<br /><br />Ginkgo not significantly different compared to placebo in double-blind study (n=487): http://www.ncbi.nlm.nih.gov/pubmed/15070635<br /><br />No evidence for Ginkgo efficacy vs. placebo in double blind study (n=57): http://www.ncbi.nlm.nih.gov/pubmed/15710792<br /><br />Source of Ginkgo may impact efficacy: http://www.ncbi.nlm.nih.gov/pubmed/19364166fkarchanoreply@blogger.comtag:blogger.com,1999:blog-3352166344614826568.post-35320456738520005632012-10-29T06:53:23.118-07:002012-10-29T06:53:23.118-07:00Jason, great post! Just an FYI, I mixed 360mg of G...Jason, great post! Just an FYI, I mixed 360mg of Gingko Biloba per day with 400mg of Ibuprofen on Denali and had unbelievable success in regards to my acclimatization. On an expedition of 5, as we checked our numbers, my oxygen level was always higher than the rest of my expedition - which when I went to 20k before, I struggled greatly without anything. I believe the Gingko Biloba really helps.Cale Hoopeshttps://www.blogger.com/profile/07165675783952647546noreply@blogger.com